In developing ProPLEXIN-CR™, ECR utilized a unique approach that targeted the problems of aging skin in a multitude of ways. Below are a list of key ingredients and their published functionality:

Argireline™(AH-3) - a neuropeptide which inhibits wrinkle formation by preventing the transmission of nerve impulses to the muscles that cause facial wrinkles. Argireline is a less invasive alternative to painful and costly injections. Laboratory tests revealed that the severity of wrinkles decreased up to 27% after 30 days of treatment.

Matrixyl 3000™ - superior to standard Matrixyl which is often referred to as "micro collagen", Matrixyl 3000™ reduces wrinkle depth by 45% after 3 months of use. Helps the skin to maintain optimum hydration, reduces the depth of existing wrinkles and helps promote collagen synthesis while keeping the skin softer and smoother.

Dermaxyl™ - reduces main wrinkle volume by 36%, helps attract cells to sites that need repair and contributes to the reconstruction of the dermis. Ceramide 2 strengthens and repairs the skin's barrier. It improves cell cohesion, enhancing water retention and reducing skin dryness.

Dermox™ - a skin resurfacing complex which increases the production of collagen and hyaluronic acid, and induces cell proliferation and differentiation. These actions make skin firmer while making deeper wrinkles less visible. Tests show that Dermox reduces the appearance of fine lines and wrinkles by 56.4% in 30 days.

Hyaluronic Acid - plays an important role in tissue hydration, lubrication and cellular function. Hyaluronic acid, often described as "nature's moisturizer", is one of the most hydrophilic (water retaining) molecules in nature and is able to hold more water than any other natural substance. Its unmatched hydrating properties result in increased smoothness, softening and decreased wrinkles.

Calmosensine™ - helps promote the release of proendorphins to provide a tranquilizing effect on the skin. Calmosensine relieves tension and inhibits the muscle contractions responsible for the formation of wrinkles and expression lines.

L-Ascorbic Acid 2 - (Glucoside) - suppresses melanin synthesis to prevent unwanted pigmentation, reduces existing melanin, resulting in a lighter pigmentation, promotes synthesis of collagen human skin fibroblasts, captures free radicals (antioxidant) and inhibits skin inflammation, suppresses UV and the effects of photo-aging.

Isoflavone™ - a collagen synthesis stimulator from soy germ and also possesses antioxidant characteristics. Tests have shown Isoflavone to increase collagen production by 29.4%.

Antarticine™ - has cryoprotective effects providing stability to proteins and lipid membranes exposed to extremes of cold or dryness. Antarticine has been shown to reduce the roughness of skin.

Elastin - provides elasticity and enables the skin to stretch.

Collagen - provides the structural framework upon which the skin is supported. Collagen provides rigidity in connective tissues and also directs the growth of new cells.

Tocopheryl Acetate (Vitamin E) - a powerful antioxidant that protects cell membranes and other fat-soluble parts of the body from free radical damage.